An international prospective cohort study of mobile phone users and health (Cosmos): design considerations and enrolment.

TitleAn international prospective cohort study of mobile phone users and health (Cosmos): design considerations and enrolment.
Publication TypeJournal Article
Year of Publication2011
AuthorsSchüz J, Elliott P, Auvinen A, Kromhout H, Poulsen A H, Johansen C, Olsen JH, Hillert L, Feychting M, Fremling K, Toledano M, Heinävaara S, Slottje P, Vermeulen R, Ahlbom A
JournalCancer Epidemiol
Volume35
Issue1
Pagination37-43
Date Published2011 Feb
ISSN1877-783X
KeywordsAdolescent, Adult, Aged, Brain Neoplasms, Cellular Phone, Cohort Studies, Electromagnetic Fields, Europe, Female, Follow-Up Studies, Humans, Male, Middle Aged, Pilot Projects, Prospective Studies, Questionnaires, Radiation, Nonionizing, Risk Assessment, Young Adult
Abstract

BACKGROUND: There is continuing public and scientific interest in the possibility that exposure to radiofrequency (RF) electromagnetic fields (EMF) from mobile telephones or other wireless devices and applications might increase the risk of certain cancers or other diseases. The interest is amplified by the rapid world-wide penetration of such technologies. The evidence from epidemiological studies published to date have not been consistent and, in particular, further studies are required to identify whether longer term (well beyond 10 years) RF exposure might pose some health risk. METHODS: The "Cosmos" study described here is a large prospective cohort study of mobile telephone users (ongoing recruitment of 250,000 men and women aged 18+ years in five European countries - Denmark, Finland, Sweden, The Netherlands, UK) who will be followed up for 25+ years. Information on mobile telephone use is collected prospectively through questionnaires and objective traffic data from network operators. Associations with disease risks will be studied by linking cohort members to existing disease registries, while changes in symptoms such as headache and sleep quality and of general well-being are assessed by baseline and follow-up questionnaires. CONCLUSIONS: A prospective cohort study conducted with appropriate diligence and a sufficient sample size, overcomes many of the shortcomings of previous studies. Its major advantages are exposure assessment prior to the diagnosis of disease, the prospective collection of objective exposure information, long-term follow-up of multiple health outcomes, and the flexibility to investigate future changes in technologies or new research questions.

DOI10.1016/j.canep.2010.08.001
Alternate JournalCancer Epidemiol
PubMed ID20810339