Influence of dose and duration of smoking on lung cancer rates.

TitleInfluence of dose and duration of smoking on lung cancer rates.
Publication TypeJournal Article
Year of Publication1986
AuthorsPeto R
JournalIARC Sci Publ
Issue74
Pagination23-33
Date Published1986
ISSN0300-5038
KeywordsAge Factors, Dose-Response Relationship, Drug, Humans, Lung Neoplasms, Risk, Smoking, Time Factors
Abstract

Lung cancer risks depend far more strongly on the duration than on the daily dose-rate of cigarette smoking. For example, a three-fold increase in the daily dose-rate may produce only about a three-fold increase in effect, while a three-fold increase in duration might produce about a 100-fold increase in effect. Hence, a few decades after cigarette smoking becomes widespread, national lung cancer rates may remain very misleadingly low, even though they will eventually become extremely high.

Alternate JournalIARC Sci. Publ.
PubMed ID3623669