Infantile spasms and neuronal heterotopias. A report on six cases.

TitleInfantile spasms and neuronal heterotopias. A report on six cases.
Publication TypeJournal Article
Year of Publication1986
AuthorsPalm L, Blennow G, Brun A
JournalActa Paediatr Scand
Volume75
Issue5
Pagination855-9
Date Published1986 Sep
ISSN0001-656X
KeywordsAbnormalities, Multiple, Autopsy, Brain, Female, Humans, Infant, Infant, Newborn, Male, Spasms, Infantile
Abstract

Six infants with infantile spasms are presented, three primarily considered idiopathic and three symptomatic. Autopsy unexpectedly revealed heterotopias, cortical dyslamination, and other brain malformations in all six cases. No history of any etiologic moment during the neuronal migratory period of early gestation was found. It is concluded that wide-spread disturbances of CNS morphology should always be considered in cases of infantile spasms.

Alternate JournalActa Paediatr Scand
PubMed ID3564953