Adult cancers near high-voltage overhead power lines.

TitleAdult cancers near high-voltage overhead power lines.
Publication TypeJournal Article
Year of Publication2013
AuthorsElliott P, Shaddick G, Douglass M, de Hoogh K, Briggs DJ, Toledano MB
JournalEpidemiology
Volume24
Issue2
Pagination184-90
Date Published03/2013
ISSN1531-5487
KeywordsAdolescent, Adult, Aged, Case-Control Studies, Electromagnetic Fields, England, Environmental Exposure, Female, Humans, Incidence, Logistic Models, Male, Middle Aged, Neoplasms, Odds Ratio, Registries, Residence Characteristics, Wales
Abstract

BACKGROUND: Extremely low-frequency magnetic fields are designated as possibly carcinogenic in humans, based on an epidemiologic association with childhood leukemia. Evidence for associations with adult cancers is weaker and inconsistent. METHODS: We conducted a case-control study to investigate risks of adult cancers in relation to distance and extremely low-frequency magnetic fields from high-voltage overhead power lines using National Cancer Registry Data in England and Wales, 1974-2008. The study included 7823 leukemia, 6781 brain/central nervous system cancers, 9153 malignant melanoma, 29,202 female breast cancer cases, and 79,507 controls frequency-matched on year and region (three controls per case except for female breast cancer, one control per case) 15-74 years of age living within 1000 m of a high-voltage overhead power line. RESULTS: There were no clear patterns of excess risk with distance from power lines. After adjustment for confounders (age, sex [except breast cancer], deprivation, rurality), for distances closest to the power lines (0-49 m) compared with distances 600-1000 m, odds ratios (ORs) ranged from 0.82 (95% confidence interval = 0.61-1.11; 66 cases) for malignant melanoma to 1.22 (0.88-1.69) for brain/central nervous system cancer. We observed no meaningful excess risks and no trends of risk with magnetic field strength for the four cancers examined. In adjusted analyses at the highest estimated field strength, ≥1000 nanotesla (nT), compared with <100 nT, ORs ranged from 0.68 (0.39-1.17) for malignant melanoma to 1.08 (0.77-1.51) for female breast cancer. CONCLUSION: Our results do not support an epidemiologic association of adult cancers with residential magnetic fields in proximity to high-voltage overhead power lines.

DOI10.1097/EDE.0b013e31827e95b9
Alternate JournalEpidemiology
PubMed ID23337237