Exposomics & Health



The main aim is to predict individual disease risk related to the environment, by characterizing the external & internal exposome for common exposures during critical periods of life, including in utero. The ultimate goal is to reduce uncertainties in risk assessment when estimating the burden of environmental disease.

Theme Leader: Professor Paolo Vineis (ICL)

Key Projects

  • The EU FP7 EXPOsOMICS study: aims to develop a new approach to assess environmental exposures, primarily focusing on air pollution (including land use regression models (LUR) and dispersion models) and water contaminants i.e. exposure to disinfection by-products (DBPs) eg. chloramines in swimming pools.
  • The Horizon 2020 LIFEPATH project: investigates the determinants of diverging ageing pathways among individuals belonging to different socio-economic groups. 
  • Envirogenomarkers: development & application of a new generation of biomarkers to study the role of environmental agents (eg. cadmium, lead, ambient air pollutants & water treatment byproducts) in human disease such as breast cancer, Non Hodgkin’s lymphoma, childhood diseases including allergy, neurological and immune diseases, thyroid disruption). Biosamples & data from 3 cohorts (Northern Sweden health & Disease Study; EPIC Italy & Rhea mother-child cohort Crete, Greece).