Found 38 results
Filters: Author is Lindon, John C  [Clear All Filters]
Pérez-Trujillo M, Lindon JC, Parella T, Keun HC, Nicholson JK, Athersuch TJ.  2012.  Chiral metabonomics: 1H NMR-based enantiospecific differentiation of metabolites in human urine via direct cosolvation with β-cyclodextrin.. Anal Chem. 84(6):2868-74.
Benton PH, Want E, Keun HC, Amberg A, Plumb RS, Goldfain-Blanc F, Walther B, Reily MD, Lindon JC, Holmes E et al..  2012.  Intra- and interlaboratory reproducibility of ultra performance liquid chromatography-time-of-flight mass spectrometry for urinary metabolic profiling.. Anal Chem. 84(5):2424-32.
Nicholson JK, Everett JR, Lindon JC.  2012.  Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy.. Expert Opin Drug Metab Toxicol. 8(2):135-9.
Nicholson JK, Holmes E, Kinross JM, Darzi AW, Takats Z, Lindon JC.  2012.  Metabolic phenotyping in clinical and surgical environments.. Nature. 491(7424):384-92.
Cunningham K, Claus SP, Lindon JC, Holmes E, Everett JR, Nicholson JK, Coen M.  2012.  Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response.. J Proteome Res. 11(9):4630-42.
Coen M, Goldfain-Blanc F, Rolland-Valognes G, Walther B, Robertson DG, Holmes E, Lindon JC, Nicholson JK.  2012.  Pharmacometabonomic investigation of dynamic metabolic phenotypes associated with variability in response to galactosamine hepatotoxicity.. J Proteome Res. 11(4):2427-40.
Fonville JM, Carter C, Cloarec O, Nicholson JK, Lindon JC, Bunch J, Holmes E.  2012.  Robust data processing and normalization strategy for MALDI mass spectrometric imaging.. Anal Chem. 84(3):1310-9.
Heinzmann SS, Merrifield CA, Rezzi S, Kochhar S, Lindon JC, Holmes E, Nicholson JK.  2012.  Stability and robustness of human metabolic phenotypes in response to sequential food challenges.. J Proteome Res. 11(2):643-55.
Maher AD, Fonville JM, Coen M, Lindon JC, Rae CD, Nicholson JK.  2012.  Statistical total correlation spectroscopy scaling for enhancement of metabolic information recovery in biological NMR spectra.. Anal Chem. 84(2):1083-91.
Posma JM, Garcia-Perez I, De Iorio M, Lindon JC, Elliott P, Holmes E, Ebbels TMD, Nicholson JK.  2012.  Subset optimization by reference matching (STORM): an optimized statistical approach for recovery of metabolic biomarker structural information from 1H NMR spectra of biofluids.. Anal Chem. 84(24):10694-701.
Zhao L, Nicholson JK, Lu A, Wang Z, Tang H, Holmes E, Shen J, Zhang X, Li JV, Lindon JC.  2012.  Targeting the human genome-microbiome axis for drug discovery: inspirations from global systems biology and traditional Chinese medicine.. J Proteome Res. 11(7):3509-19.
Cazier J-B, Kaisaki PJ, Argoud K, Blaise BJ, Veselkov K, Ebbels TMD, Tsang T, Wang Y, Bihoreau M-T, Mitchell SC et al..  2012.  Untargeted metabolome quantitative trait locus mapping associates variation in urine glycerate to mutant glycerate kinase.. J Proteome Res. 11(2):631-42.
Legido-Quigley C, McDermott L, Vilca-Melendez H, Murphy GM, Heaton N, Lindon JC, Nicholson JK, Holmes E.  2011.  Bile UPLC-MS fingerprinting and bile acid fluxes during human liver transplantation.. Electrophoresis. 32(15):2063-70.
Claus SP, Ellero SL, Berger B, Krause L, Bruttin A, Molina J, Paris A, Want EJ, de Waziers I, Cloarec O et al..  2011.  Colonization-induced host-gut microbial metabolic interaction.. MBio. 2(2):e00271-10.
Sands CJ, Coen M, Ebbels TMD, Holmes E, Lindon JC, Nicholson JK.  2011.  Data-driven approach for metabolite relationship recovery in biological 1H NMR data sets using iterative statistical total correlation spectroscopy.. Anal Chem. 83(6):2075-82.
Nicholson G, Rantalainen M, Li JV, Maher AD, Malmodin D, Ahmadi KR, Faber JH, Barrett A, Min JL, Rayner WN et al..  2011.  A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.. PLoS Genet. 7(9):e1002270.
Spagou K, Wilson ID, Masson P, Theodoridis G, Raikos N, Coen M, Holmes E, Lindon JC, Plumb RS, Nicholson JK et al..  2011.  HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies.. Anal Chem. 83(1):382-90.
Nicholson G, Rantalainen M, Maher AD, Li JV, Malmodin D, Ahmadi KR, Faber JH, Hallgrímsdóttir IB, Barrett A, Toft H et al..  2011.  Human metabolic profiles are stably controlled by genetic and environmental variation.. Mol Syst Biol. 7:525.
Edmands WMB, Beckonert OP, Stella C, Campbell A, Lake BG, Lindon JC, Holmes E, Gooderham NJ.  2011.  Identification of human urinary biomarkers of cruciferous vegetable consumption by metabonomic profiling.. J Proteome Res. 10(10):4513-21.
Merrifield CA, Lewis M, Claus SP, Beckonert OP, Dumas M-E, Duncker S, Kochhar S, Rezzi S, Lindon JC, Bailey M et al..  2011.  A metabolic system-wide characterisation of the pig: a model for human physiology.. Mol Biosyst. 7(9):2577-88.