Found 27 results
Filters: Author is Keun, Hector C  [Clear All Filters]
Jiménez B, Mirnezami R, Kinross J, Cloarec O, Keun HC, Holmes E, Goldin RD, Ziprin P, Darzi A, Nicholson JK.  2013.  1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication.. J Proteome Res. 12(2):959-68.
Blazquez M, Carretero A, Ellis JK, Athersuch TJ, Cavill R, Ebbels TMD, Keun HC, Castell JV, Lahoz A, Bort R.  2013.  A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR).. J Proteome Res. 12(6):2732-41.
Athersuch TJ, Wilson ID, Keun HC, Lindon JC.  2013.  Development of quantitative structure-metabolism (QSMR) relationships for substituted anilines based on computational chemistry.. Xenobiotica. 43(9):792-802.
Athersuch TJ, Malik S, Weljie A, Newton J, Keun HC.  2013.  Evaluation of 1H NMR metabolic profiling using biofluid mixture design.. Anal Chem. 85(14):6674-81.
Ramirez T, Daneshian M, Kamp H, Bois FY, Clench MR, Coen M, Donley B, Fischer SM, Ekman DR, Fabian E et al..  2013.  Metabolomics in toxicology and preclinical research.. ALTEX. 30(2):209-25.
Hebels DGAJ, Georgiadis P, Keun HC, Athersuch TJ, Vineis P, Vermeulen R, Portengen L, Bergdahl IA, Hallmans G, Palli D et al..  2013.  Performance in omics analyses of blood samples in long-term storage: opportunities for the exploitation of existing biobanks in environmental health research.. Environ Health Perspect. 121(4):480-7.
Cavill R, Kamburov A, Ellis JK, Athersuch TJ, Blagrove MSC, Herwig R, Ebbels TMD, Keun HC.  2011.  Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells.. PLoS Comput Biol. 7(3):e1001113.
Teichert F, Winkler S, Keun HC, Steward WP, Gescher AJ, Farmer PB, Singh R.  2011.  Evaluation of urinary ribonucleoside profiling for clinical biomarker discovery using constant neutral loss scanning liquid chromatography/tandem mass spectrometry.. Rapid Commun Mass Spectrom. 25(14):2071-82.
Kamburov A, Cavill R, Ebbels TMD, Herwig R, Keun HC.  2011.  Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA.. Bioinformatics. 27(20):2917-8.
Chadeau-Hyam M, Athersuch TJ, Keun HC, De Iorio M, Ebbels TMD, Jenab M, Sacerdote C, Bruce SJ, Holmes E, Vineis P.  2011.  Meeting-in-the-middle using metabolic profiling - a strategy for the identification of intermediate biomarkers in cohort studies.. Biomarkers. 16(1):83-8.
Keun HC, Athersuch TJ.  2011.  Nuclear magnetic resonance (NMR)-based metabolomics.. Methods Mol Biol. 708:321-34.
Spurgeon DJ, Lawlor A, Hooper HL, Wadsworth R, Svendsen C, Thomas LDK, Ellis JK, Bundy JG, Keun HC, Jarup L.  2011.  Outdoor and indoor cadmium distributions near an abandoned smelting works and their relations to human exposure.. Environ Pollut. 159(12):3425-32.
Backshall A, Sharma R, Clarke SJ, Keun HC.  2011.  Pharmacometabonomic profiling as a predictor of toxicity in patients with inoperable colorectal cancer treated with capecitabine.. Clin Cancer Res. 17(9):3019-28.